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Important mechanism identified in the formation of blood vessels
Tumors cannot grow to more than 1-2mm without new blood vessels. Antibodies against VEGFterm such as Avastinterm have been shown to be effective in slowing the growth of tumors by inhibiting the...
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Reasons Why Cancer Drug Discovery is so Difficult
   In the perspective article in Nature Reviews Drug Discovery, the authors discuss the challenges facing drug discovery as intricate and numerous. They present a broad picture of drug discovery...
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EntreMed Starts Phase II Clinical Trial of Panzem with Sutent for Kidney...
   EntreMed, Inc has commenced a Phase 2 trial to evaluate the safety and efficacy of Panzem (2-methoxyestradiol; 2ME2) alone or in combination with Sutenttermterm (sunitinibterm) in patients with...
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Targeting sugar on blood vessels may inhibit cancer growth
In a study that could point to novel therapies to prevent cancer spread, or metastasistermterm, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar...
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St. Jude study shows temporary improvement of tumor blood flow can improve...
A treatment for neuroblastoma that lands a one-two punch works best when the second punch is timed to take maximum advantage of the first one, according to results of studies at St. Jude Children’s...
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Study finds blocking angiogenesis signaling from inside cell may lead to...
'Extremely surprising' outcome may result in more caution in use of angiogenesis drugsAngiogenesis inhibitors that block a tumor’s development of an independent blood supply have been touted as...
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Study shows blood markers can help choose best dose for antiangiogenic drugs
Scientists at Sunnybrook have new information that may help to improve the use of anti-cancer drugs designed to block the growth of new blood vessels in tumors, a process called angiogenesis that is...
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Lymphatic vessel and lymph node function are restored with growth factor...
The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system and can cause lymphedema, a condition of localized fluid...
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Precancerous Stem Cells Can Form Tumor Blood Vessels
COLUMBUS, Ohio – Tumors require a blood supply to grow, but how they acquire their network of blood vessels is poorly understood. A new study here shows that tumor blood vessels can develop from...
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Mayo Clinic study shows Parkinson's disease drug might work in cancer patients
ROCHESTER, Minn. -- A study published in the March 13 online issue of The Journal of Clinical Investigation shows that dopamine, a drug currently used to treat Parkinson’s disease and other...
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